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A study to assess the efficacy and safety of dazodalibep in Sjögren's disease
A study to assess the efficacy and safety of the CD40 ligand antagonist dazodalibep in Sjögren's disease
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An interactive webapp for exploring systemic lupus erythematosus blood transcriptomic diversity
Resulting from a multi-team collaboration, the LUPUCE webapp has been developed as a tool to explore blood transcriptomic data in systemic lupus erythematosus.
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New article in Nature Review in Rheumatology
Immune-checkpoint inhibitor use in patients with cancer and pre-existing autoimmune diseases
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A giant step forward for the treatment of patients with PPR
New publication from LBAI-UMR1227 in JAMA: blocking IL-6 using tocilizumab has a strong steroid-sparing effect in Polymyalgia Rheumatica
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New publication in Nature Communications
A new molecular classification to drive precision treatment strategies in primary Sjögren's syndrome
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Machine learning identifies a common signature for anti-SSA/Ro60 antibody expression across autoimmune diseases
Autoantibodies are markers of autoimmune diseases. The most frequently observed is the anti-SSA/Ro autoantibody. It is observed in Gougerot-Sjögren syndrome, systemic lupus erythematosus, undifferentiated connectivites but also sometimes in rheumatoid arthritis and scleroderma. Using artificial intelligence approaches on multi-omics data [...]
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Presentation of Anthony Mainguy, PhD student at LBAI
Anthony Mainguy joined the LBAI in 2020 to carry on a thesis project on the Implication of calcium signaling in the differentiation and functional orientation of the B lymphocyte. Watch a presentation video...